VCT 2021 NA Stage 3 Challengers Playoffs was held from August 13th-22nd 2021, featuring 16 teams competing for the $100,000 prize pool. It had 2 main phases: Group Stage, from August 13th to 16th,  and playoffs stage, from August 19th to 22nd. The format of the playoffs is a double elimination bracket with matches before Grand Finals in Best-of-3, while the Grand Finals in Best-of-5. The tournament handed 2 top teams a spot for the VCT Masters Berlin.

VCT SEA Stage 3 Challengers Playoffs was held in assistance with Mineski and ESL Thailand.

The winner of the tournament was Bren Esports, who took home $25,000 as a prize. The second-placed team was Paper Rex, which also earned the right to participate at Masters Berlin 2021.

The viewership stats of the tournament showed peak viewers of 60,340, while the average was 23,274 views.